MRI studies reported that ALS patients with bulbar and spinal onset showed focal cortical changes in corresponding regions of the motor homunculus. We evaluated the capability of brain 2-[18F]FDG-PET to disclose the metabolic features characterizing patients with pure bulbar or spinal motor impairment.
Brain metabolic differences between pure bulbar and pure spinal ALS: a 2-[18F]FDG-PET study / Canosa, Antonio; Martino, Alessio; Giuliani, Alessandro; Moglia, Cristina; Vasta, Rosario; Grassano, Maurizio; Palumbo, Francesca; Cabras, Sara; Di Pede, Francesca; De Mattei, Filippo; Matteoni, Enrico; Polverari, Giulia; Manera, Umberto; Calvo, Andrea; Pagani, Marco; Chiò, Adriano. - In: JOURNAL OF NEUROLOGY. - ISSN 0340-5354. - 270:2(2023), pp. 953-959. [10.1007/s00415-022-11445-9]
Brain metabolic differences between pure bulbar and pure spinal ALS: a 2-[18F]FDG-PET study
Martino, Alessio;
2023
Abstract
MRI studies reported that ALS patients with bulbar and spinal onset showed focal cortical changes in corresponding regions of the motor homunculus. We evaluated the capability of brain 2-[18F]FDG-PET to disclose the metabolic features characterizing patients with pure bulbar or spinal motor impairment.
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